PRX-PLUS in Palm Springs & Rancho Mirage

PRX-PLUS is a needle-free, in-office skin booster that targets deep wrinkles, enlarged pores, and uneven pigment without the downtime of a traditional peel. Patients who choose PRX-PLUS in Palm Springs enjoy smoother, brighter, firmer-looking skin.

Advanced Skin Renewal Guided by a Plastic Surgeon's Eye

Dr. Mark Sofonio, MD, FACS, offers PRX-PLUS at Sofonio Aesthetics for patients who want visible skin renewal without needles or recovery time. As a board-certified plastic surgeon, he evaluates skin the same way he plans surgery: with attention to anatomy, balance, and natural-looking results. Each PRX-PLUS plan at his Rancho Mirage clinic is built around your skin's specific concerns. PRX-PLUS treatments are performed by the practice's experienced estheticians.

What Is PRX-PLUS?

PRX-PLUS is a professional skin treatment from WiQo, the Italian maker of the PRX line. According to WiQo, PRX-PLUS is a clinician-performed skin booster designed for mature or textured skin showing visible signs of aging.

The patented PRX-PLUS formula combines:

Ammonium trichloroacetate (ATCA): A modified form of trichloroacetic acid (TCA), a well-established skin-renewal ingredient
Homocysteic acid: An ingredient that works alongside ATCA to support brightening and renewal
Citric and phytic acids: Supporting acids that complete the formulation

Traditional TCA peels work by removing damaged outer layers of skin, which can mean days of peeling and recovery, as Cleveland Clinic notes. WiQo classifies PRX-PLUS as a skin booster instead, designed to improve skin quality without that downtime.

Are You a Candidate for PRX-PLUS?

PRX-PLUS is best suited to adults with mature, thicker, or sun-damaged skin who want more visible renewal than a facial provides. WiQo designed it for skin showing deep wrinkles, enlarged pores, and hyperpigmentation. The company also reports that PRX treatments are effective across skin tones and types.

You may need to postpone PRX-PLUS if you:

Have an active rash, sunburn, open wound, or skin infection
Are experiencing a cold sore outbreak
Are currently using or recently used isotretinoin (Accutane)
Are pregnant or nursing

Patients who prefer a treatment focused on dullness and radiance may be better suited to PRX C. Dr. Sofonio's team will help you choose.

Why Choose Sofonio Aesthetics for PRX-PLUS in Palm Springs?

Your dermaClae treatment is performed by Jon Poling, P.A., a physician assistant who serves as a National Trainer for dermaClae. In that role, he helps teach other providers how to use the product, so patients benefit from his hands-on expertise with dermaClae and its technique. Dr. Sofonio has dedicated his career to creating results that look refreshed, never overdone. He completed the accelerated UCR/UCLA combined undergraduate and medical school program with Magna Cum Laude honors. His patient care has earned recognition from Southern California Super Doctors® and multiple Best of Desert awards. That combined surgical and product expertise matters with a fat-based treatment.

Knowing where facial fat pads sit and how they shift with age helps our team place dermaClae for balanced, natural-looking results. Your dermaClae treatment is performed by Jon Poling, P.A., a physician assistant who serves as a National Trainer for dermaClae. In that role, he helps teach other providers how to use the product, so patients benefit from his hands-on expertise with dermaClae and its technique. Patients also benefit from a broad range of treatments under one roof. Sofonio Aesthetics offers lasers, radiofrequency microneedling, ultrasound skin tightening, and injectables, so PRX-PLUS can fit into a complete rejuvenation plan. Dr. Sofonio's work has been recognized by Southern California Super Doctors® and Best of Desert awards from 2021 to 2024.

What to Expect Before, During, and After PRX-PLUS

Consultation and Cost of PRX-PLUS

Your PRX-PLUS journey starts with a consultation at our Rancho Mirage clinic. Our team will examine your skin, discuss your goals, and recommend the number of sessions you may need. Cost depends on the treatment area and whether you choose a single session or a series. Please contact us for current pricing.

The PRX-PLUS Treatment Experience

Treatment begins with cleansing and preparing the skin. Your esthetician then applies PRX-PLUS in layers using WiQo's specific technique, which involves working the solution into the skin. You may feel mild warmth or tingling during application. A session typically lasts about 20–30 minutes.

PRX-PLUS Results and Aftercare

Following your session, your esthetician will send you home with aftercare instructions, which may include a specific moisturizer. Daily sun protection is essential in the desert climate. The American Academy of Dermatology recommends a broad-spectrum sunscreen with SPF 30 or higher. Following your session, your provider will send you home with aftercare instructions, which may include a specific moisturizer. Daily sun protection is essential in the desert climate. The American Academy of Dermatology recommends a broad-spectrum sunscreen with SPF 30 or higher.

PRX-PLUS vs. Traditional Chemical Peels

The main difference between PRX-PLUS and a traditional chemical peel is recovery. Medium and deep peels remove layers of skin to reveal fresh skin beneath, and deeper peels need longer healing time. PRX-PLUS is designed to renew the skin's appearance without visible peeling, so most patients return to normal activities right away.

For patients with more advanced sun damage, a custom chemical peel or CO2 laser resurfacing may still be the stronger choice. Dr. Sofonio will explain which option fits your skin and schedule.

Treatments That Pair Well With PRX-PLUS

PRX-PLUS can be combined with other treatments at Sofonio Aesthetics for more complete rejuvenation:

INTRAcel RF Microneedling for deeper texture and firmness concerns
IPL and Cutera Laser Photofacial for sun spots and redness
Sofwave for non-surgical lifting and tightening
Neurotoxins and facial fillers for expression lines and lost volume

PRX-PLUS FAQs

Is PRX-PLUS a Chemical Peel?

WiQo describes PRX-PLUS as a professional skin booster rather than a traditional peel. Although it contains a modified form of TCA, it is designed to improve skin quality without visible peeling or downtime.

Does PRX-PLUS Hurt?

PRX-PLUS is needle-free and generally well tolerated. Most patients feel mild warmth, tingling, or tightness during application, which fades after treatment.

Can I Get PRX-PLUS in the Summer?

Yes, according to WiQo, PRX treatments can be performed any time of year. Year-round sunscreen is still essential in the Coachella Valley.

What Is the Difference Between PRX-PLUS and PRX C?

PRX-PLUS targets mature or textured skin with deep wrinkles, enlarged pores, and pigment concerns. PRX C adds vitamin C and focuses on dull, tired, or environmentally stressed skin. Our team will recommend the best match for your skin.

What Are the Risks and Side Effects of PRX-PLUS?

PRX-PLUS is designed to have minimal side effects. Some patients notice temporary redness, dryness, or tightness. Share your full skin history and medications with our team before treatment so we can plan safely.

Schedule PRX-PLUS at Sofonio Aesthetics in Rancho Mirage

Discover what needle-free skin renewal can do for you. Schedule a consultation or call (760) 388-6677. Patients looking for PRX-PLUS in Palm Springs, Palm Desert, and La Quinta trust Dr. Sofonio for natural-looking, personalized results.

This information is provided for educational purposes only and does not replace a consultation with a board-certified plastic surgeon. Outcomes, risks, and suitability vary from patient to patient.

Sources

WiQo: PRX-PLUS
WiQo: PRX Skin Treatment
Cleveland Clinic: Chemical Peels
American Academy of Dermatology: How to Select a Sunscreen